GSM1160022[Accession] - GEO DataSets

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Items: 4

Select item 2000478191.

Epigenetic and genetic changes during mouse hematopoietic stem cell aging

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL13112
37 Samples

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Series

Accession:: GSE47819

ID:: 200047819

PubMed Full text in PMC Similar studies

Select item 2000478152.

Epigenetic and genetic changes during mouse hematopoietic stem cell aging [Bisulfite-Seq]

(Submitter supplied) To investigate the global DNA methylation changes in mouse hematopoietic stem cell aging, we performed whole-genome bisulfite sequencing (WGBS). We generated 1,494 million (4mo HSCs), and 1,493 million (24mo HSCs) raw reads; about 82.6% and 84.3%, respectively, were successfully aligned to either strand of the reference genome (mm9). Of all the cytosines present in the reference genome sequence, about 93% of Cs and 99% of CGs were covered in both datasets, with an average coverage of 46-fold (4mo) and 50-fold (24mo). more...