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Items: 4

1.

PRC2 coordinates lineage fidelity and DNA methylation during ESC differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL11002
37 Samples
Download data: WIG
Series
Accession:
GSE53508
ID:
200053508
2.

PRC2 coordinates lineage fidelity and DNA methylation during ESC differentiation (RRBS)

(Submitter supplied) Polycomb Repressive Complex 2 (PRC2) catalyzes histone H3 lysine 27 tri-methylation, an epigenetic modification associated with gene repression. H3K27me3 is enriched at the promoters of a large cohort of developmental genes in embryonic stem cells (ESCs). Loss of H3K27me3 leads to a failure of ESCs to properly differentiate, which presents a major roadblock for dissecting the precise roles of PRC2 activity during lineage commitment. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL13112
16 Samples
Download data
Series
Accession:
GSE53507
ID:
200053507
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

Suz12Dd5-1_RRBS

Organism:
Mus musculus
Source name:
in vitro differentiated cells
Platform:
GPL13112
Series:
GSE53507 GSE53508
Download data
Sample
Accession:
GSM1295064
ID:
301295064
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Supplemental Content

db=gds|term=GSM1295064[Accession]|query=1|qty=2|blobid=MCID_67571906fd45205cc52f3500|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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