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Items: 3

1.

PI3Kδ Inhibition Modulates the Innate Inflammatory Response in Pancreatic Ductal Adenocarcinoma and Normalizes Aberrant Metabolism Associated with Cachexia

(Submitter supplied) PDAC is an inflammatory disease in urgent need of effective therapeutic intervention. The PI3K p110δ isform inhibition resulted in sustained survival rarely seen in KPC mouse model of pancreatic cancer. The single agent therapy significantly decreased tumor burden, differentially regulated tumour inflammatory and metabolic transcirptome profile and normalized muscle metabolic response associated with cachexia.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
26 Samples
Download data: TXT
Series
Accession:
GSE59757
ID:
200059757

SRA Run Selector

2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8394 Series
189339 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

PMNs sorted from spleen, low_vehicle3

Organism:
Mus musculus
Source name:
PMNs sorted from spleen
Platform:
GPL13112
Series:
GSE59757
Download data: TXT
Sample
Accession:
GSM1446143
ID:
301446143

SRA Run Selector

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db=gds|term=GSM1446143[Accession]|query=1|qty=2|blobid=MCID_679200b93ebf211704ad8e50|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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