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Items: 3

1.

Cross-species comparative analysis of Dicer proteins during Sindbis virus infection

(Submitter supplied) The role of RNA silencing as a defense mechanism against viruses remains to be formerly established in mammalian somatic cells. Here, we determined the antiviral properties of human and Drosophila Dicer proteins in a heterologous setup. We expressed human Dicer (hDicer) in Drosophila, and Drosophila Dicer-2 in human cells, and measured the impact on the response to Sindbis virus (SINV) infection. In flies, hDicer presents a low processing activity, but partially rescues a Dcr2 null mutation in flies. more...
Organism:
Homo sapiens; Sindbis virus; Drosophila melanogaster
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL19381 GPL19380
11 Samples
Download data: BED, TXT
Series
Accession:
GSE62934
ID:
200062934

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens; Sindbis virus)

Organism:
Homo sapiens; Sindbis virus
1 Series
8 Samples
Download data
Platform
Accession:
GPL19381
ID:
100019381

3.

sRNAs from SINV-infected HEK293 cells expressing DAR (=Dicer-2 and R2D2), 16 hpi

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293 cell line
Platform:
GPL19381
Series:
GSE62934
Download data: BED, TXT
Sample
Accession:
GSM1536635
ID:
301536635

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db=gds|term=GSM1536635[Accession]|query=1|qty=4|blobid=MCID_678f61eaf521160690464313|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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