GSM1555177[Accession] - GEO DataSets

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Items: 4

Select item 2000636831.

iBET resistance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL6887
35 Samples

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Series

Accession:: GSE63683

ID:: 200063683

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000636822.

ChIP of BET proteins in iBET resistance [ChIP-seq]

(Submitter supplied) Bromodomain and Extra Terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic paradigm by directly targeting epigenetic readers1,2. Early clinical trials have shown significant promise especially in acute myeloid leukaemia (AML)3; therefore the evaluation of resistance mechanisms, an inevitable consequence of cancer therapies, is of utmost importance to optimise the clinical efficacy of these drugs. more...