GSM1608254[Accession] - GEO DataSets

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Items: 3

Select item 2000658831.

Genome-wide association of Sus1 with RNAPII and tRNA genes depends on the distinctive SAGA subunits Spt8 and Spt7

(Submitter supplied) We have analyzed the global effect of the conserved transcription-mRNA export factor Sus1 on transcription and its association with chromatin. We used genomic run-on experiments to show that Sus has a broad impact on the stability of most RNA polymerase II-transcribed genes. Genome association of Sus1 by the chromatin immunoprecipitation technique showed that Sus1 was widely distributed throughout coding regions, tending to accumulate towards the 3’ ends of highly transcribed transcription factor IID (TFIID) and Spt-Ada-Gcn5 acetyltransferase (SAGA) dependent genes. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by genome tiling array

Platform:: GPL19774
12 Samples

Download data: BAR, CEL

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Accession:: GSE65883

ID:: 200065883

Select item 1000197742.

[Scerevisiae_tlg] Affymetrix Saccharomyces cerevisiae tiling array

(Submitter supplied) The platform contains 25 nucleotide probes spaced every 8 bp covering one strand of the whole /Saccharomyces cerevisiae/ genome sequence and a second set of probes offset 4 bp from the first set to cover the other strand. Lee et al. (2007) Nature Genetics 39: 1235-1244. Protocol: see manufacturer's web site