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Items: 3

1.

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX

(Submitter supplied) Maintenance of chromatin homeostasis involves proper delivery of histone variants to the genome. The interplay between different chaperones regulating the supply of histone variants to distinct chromatin domains remains largely undeciphered. We report a role of promyelocytic leukemia (PML) protein in the routing of histone variant H3.3 to chromatin and in the organization of megabase-size heterochromatic PML-associated domains that we call PADs. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL17021 GPL19057
20 Samples
Download data: BED, BW, CSV
Series
Accession:
GSE66364
ID:
200066364
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

PMLKO_H3K27me3

Organism:
Mus musculus
Source name:
Mouse embryonic fibroblasts, PML knock-out
Platform:
GPL17021
Series:
GSE66364
Download data: BED, BW
Sample
Accession:
GSM1621018
ID:
301621018
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