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Items: 4

1.

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus hominis; Human alphaherpesvirus 2; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platforms:
GPL20657 GPL20658
12 Samples
Download data: TXT
Series
Accession:
GSE70996
ID:
200070996
2.

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 13]

(Submitter supplied) Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL) the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cells engage and recruit nurturing cells is poorly characterised. Here we demonstrate that CLL cells secrete exosomes that are nanovesicles originating from the fusion of multivesicular bodies with the plasma membrane, to shuttle proteins, lipids, microRNAs (miR) and mRNAs to recipient cells. more...
Organism:
Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8
Type:
Non-coding RNA profiling by array
Platform:
GPL20657
6 Samples
Download data: TXT
Series
Accession:
GSE70994
ID:
200070994
3.

miRCURY LNA microRNA Array, v.11.0 - hsa, mmu & rno, miRBase 13.0

(Submitter supplied) See Exiqon website
Organism:
Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human betaherpesvirus 6B; Human gammaherpesvirus 8; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae
2 Series
6 Samples
Download data
Platform
Accession:
GPL20657
ID:
100020657
4.

CLL Exosomal RNA 1

Organism:
Homo sapiens
Source name:
RNA extracted from exosomes isolated from CLL culture medium patient 1 (channel 1) Pooled reference sample (channel 2)
Platform:
GPL20657
Series:
GSE70994 GSE70996
Download data: TXT
Sample
Accession:
GSM1824820
ID:
301824820
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Supplemental Content

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