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Items: 3

1.

High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism

(Submitter supplied) Dietary folate is a major source of methyl groups required for DNA methylation, an epigenetic modification that is actively maintained and remodelled during spermatogenesis. While high dose folic acid supplementation (up to ten times the daily recommended dose) has been shown to improve sperm parameters in infertile men, the effects of supplementation on the sperm epigenome are unknown. To assess the impact of six months of high dose folic acid supplementation on the sperm epigenome, we studied 30 men with idiopathic infertility. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
56 Samples
Download data: TXT
Series
Accession:
GSE72606
ID:
200072606

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10525 Series
183376 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

7_Before

Organism:
Homo sapiens
Source name:
Sperm
Platform:
GPL11154
Series:
GSE72606
Download data
Sample
Accession:
GSM1866008
ID:
301866008

SRA Run Selector

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db=gds|term=GSM1866008[Accession]|query=1|qty=2|blobid=MCID_67097ae8475a635e85abe67d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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