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Items: 4

1.

Reconstructing gene regulatory networks of tumorigenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; SNP genotyping by SNP array; Genome variation profiling by SNP array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL3718 GPL11154 GPL6244
27 Samples
Download data: BED, BW, CEL, WIG
Series
Accession:
GSE72533
ID:
200072533
2.

Reconstructing gene regulatory networks of tumorigenesis [SNP]

(Submitter supplied) The mechanistic links between transcription factors and the epigenetic landscape, which coordinate the deregulation of gene networks during cell transformation are largely unknown. We used an isogenic model of stepwise tumorigenic transformation of human primary cells to monitor the progressive deregulation of gene networks upon immortalization and oncogene-induced transformation. By combining transcriptome and epigenome data for each step during transformation and by integrating transcription factor (TF) - target gene associations, we identified 142 TFs and 24 chromatin remodelers/modifiers (CRMs), which are preferentially associated with specific co-expression paths that originate from deregulated gene programming during tumorigenesis. more...
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array; Genome variation profiling by SNP array
Platform:
GPL3718
3 Samples
Download data: CEL, TXT
Series
Accession:
GSE72531
ID:
200072531
3.

[Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip® Human Mapping 500K Array Set provides consistently high coverage across different populations. It is comprised of two arrays, each capable of genotyping on average 250,000 SNPs (approximately 262,000 for Nsp arrays and 238,000 for Sty arrays). more...
Organism:
Homo sapiens
193 Series
11192 Samples
Download data
Platform
Accession:
GPL3718
ID:
100003718
4.

BJEL_SNP_Affy_250K

Organism:
Homo sapiens
Source name:
Immortalized BJEL fibroblast cells (pretransformed)
Platform:
GPL3718
Series:
GSE72531 GSE72533
Download data: CEL
Sample
Accession:
GSM1868967
ID:
301868967
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