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Items: 4

1.

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
22 Samples
Download data: CSV
Series
Accession:
GSE75632
ID:
200075632
2.

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation (ChIP-Seq)

(Submitter supplied) In this work we compare the molecular functions of Myf5 and MyoD, two highly related bHLH transcription factors that regulate skeletal muscle specification and differentiation. We find MyoD and Myf5 bind the same sites genome-wide but have distinct functions: Myf5 induces histone acetylation without Pol II recruitment or robust gene activation, whereas MyoD induces histone acetylation, recruits PolII and robustly activates gene transcription.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
10 Samples
Download data: CSV
Series
Accession:
GSE75370
ID:
200075370
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

H4Ac_Myf5

Organism:
Mus musculus
Source name:
ChIP-Seq with H4Ac antibody 39925 in mouse M&M MEF cells transduced with Myf5
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954035
ID:
301954035
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Supplemental Content

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