U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 3

1.

Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington’s disease mice.

(Submitter supplied) Huntington’s disease (HD) is an inherited neurodegenerative disorder of which skeletal muscle atrophy is a common feature, and multiple lines of evidence support a muscle-based pathophysiology in HD mouse models. Inhibition of myostatin signaling increases muscle mass, and therapeutic approaches based on this are in clinical development. We have used a soluble ActRIIB decoy receptor (ACVR2B/Fc) to test the effects of myostatin/activin A inhibition in the R6/2 mouse model of HD. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
80 Samples
Download data: XLSX
Series
Accession:
GSE81367
ID:
200081367

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8331 Series
188429 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

R6/2 ActRIIB Quadriceps mRNA rep3

Organism:
Mus musculus
Source name:
Quadriceps Muscle
Platform:
GPL13112
Series:
GSE81367
Download data
Sample
Accession:
GSM2151224
ID:
302151224

SRA Run Selector

Format
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSM2151224[Accession]|query=1|qty=2|blobid=MCID_6705aa01c15063368027dfbb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center