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Items: 4

1.

Genomic integration of Wnt/b-catenin and BMP/Smad1 coordinates the transcriptional program of foregut and hindgut progenitors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Xenopus laevis
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL18936
57 Samples
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Series
Accession:
GSE87654
ID:
200087654
2.

Genomic integration of Wnt/b-catenin and BMP/Smad1 coordinates the transcriptional program of foregut and hindgut progenitors [ChIP-seq]

(Submitter supplied) Digestive system development is orchestrated by combinatorial signaling interactions between endoderm and mesoderm, but how they are integrated in the genome is poorly understood. Here we identified the Xenopus foregut and hindgut progenitor transcriptomes, which are largely conserved with mammals. Using RNA-seq and ChIP-seq we show that BMP/Smad1 regulates dorsal-ventral gene expression in both the endoderm and mesoderm, whereas Wnt/b-catenin acts as a genome-wide toggle between foregut and hindgut programs. more...
Organism:
Xenopus laevis
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18936
20 Samples
Download data: BED
Series
Accession:
GSE87652
ID:
200087652
3.

Illumina HiSeq 2500 (Xenopus laevis)

Organism:
Xenopus laevis
40 Series
520 Samples
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Platform
Accession:
GPL18936
ID:
100018936
4.

Input_for_p300_FG_BIO

Organism:
Xenopus laevis
Source name:
Foregut explants
Platform:
GPL18936
Series:
GSE87652 GSE87654
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Sample
Accession:
GSM2337685
ID:
302337685
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Supplemental Content

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