GSM246460[Accession] - GEO DataSets

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Items: 3

Select item 2000097711.

A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation

(Submitter supplied) Histone acetylation and deacetylation are among the principal mechanisms by which chromatin is regulated during transcription, DNA silencing, and DNA repair. We analyzed patterns of genetic interactions uncovered during comprehensive genome-wide analyses in yeast to probe how histone acetyltransferase (HAT) and histone deacetylase (HDAC) protein complexes interact. The genetic interaction data unveil an underappreciated role of HDACs in maintaining cellular viability, and led us to show that deacetylation of the histone variant Htz1p at lysine 14 is mediated by Hda1p. more...

Organism:: Saccharomyces cerevisiae

Type:: Other

Platform:: GPL1444
44 Samples

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Series

Accession:: GSE9771

ID:: 200009771

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000014442.

Hopkins Tag Array

(Submitter supplied) Comprehensive array of all 6018 UpTag/DnTag pairs designed for incorporation into yeast deletion strains by the Yeast Deletion Project (June 2002). Custom-designed negative and positive controls comprise almost half of the 215x105 array. Keywords = yeast, deletion, knockout, tag, barcode, synthetic, control, oligonucleotide

Organism:: Saccharomyces cerevisiae

16 Series
218 Samples

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Platform

Accession:: GPL1444

ID:: 100001444

PubMed Full text in PMC Similar studies

Select item 3002464603.

Genetic interactions involving the esa1-531 query mutation at 31 degrees C

Organism:: Saccharomyces cerevisiae

Source name:: Cells selected for the query mutation (channel 1) A matched aliquot of cells, grown in parallel but without selection for the query mutation (channel 2)