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Items: 3

1.

Mapping DNA methylation and CTCF/cohesin occupancy on nascent chromatin and DNMT-targeted nascent chromatin

(Submitter supplied) The faithful inheritance of the epigenome is critical for cells to maintain gene expression programs and cellular identity across cell divisions. We mapped strand-specific DNA methylation after replication forks and show maintenance of the vast majority of the DNA methylome within 20 minutes of replication and inheritance of some hemimethylated CpG dinucleotides (hemiCpGs). Mapping the nascent DNA methylome targeted by each of the three DNA methyltransferases (DNMTs) reveals interactions between DNMTs and substrate daughter cytosines en route to maintenance methylation or hemimethylation. more...
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL17021 GPL16791
53 Samples
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Series
Accession:
GSE97394
ID:
200097394
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

nasChIP-BS-seq_DNMT1_chase_daughter_rep1

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL16791
Series:
GSE97394
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Sample
Accession:
GSM2563808
ID:
302563808
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