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Items: 4

1.

JQ1 prevents BRD4 recruitment to the lytic origins of replication [Akata-Zta DNA-seq]

(Submitter supplied) Lytic infection by the Epstein-Barr virus (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative disorder. We demonstrate that JQ1 and other BET inhibitors block two different steps in the sequential cascade of the EBV life cycle: expression of the immediate-early gene BZLF1 and lytic genome replication. This represents a novel mode of action for antiviral drugs that may increase efficacy and decrease emergence of resistance. more...
Organism:
human gammaherpesvirus 4; Homo sapiens
Type:
Other
Platform:
GPL23362
8 Samples
Download data: WIG
Series
Accession:
GSE98772
ID:
200098772

PubMed Full text in PMC Similar studies SRA Run Selector

2.

BET inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
human gammaherpesvirus 4; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL23362 GPL22131 GPL22132
106 Samples
Download data: WIG
Series
Accession:
GSE84214
ID:
200084214

PubMed Full text in PMC Similar studies

3.

Illumina HiSeq 4000 (Homo sapiens; Human gammaherpesvirus 4)

Organism:
Homo sapiens; human gammaherpesvirus 4
10 Series
52 Samples
Download data
Platform
Accession:
GPL23362
ID:
100023362

4.

TotalDNA-seq_Akata-Zta+acy+JQ1_LGNFR+_Replicate1

Organism:
human gammaherpesvirus 4; Homo sapiens
Source name:
Akata-Zta cells
Platform:
GPL23362
Series:
GSE84214 GSE98772
Download data: WIG
Sample
Accession:
GSM2611568
ID:
302611568

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db=gds|term=GSM2611568[Accession]|query=1|qty=3|blobid=MCID_66dc8532ebdbf01cbf2cf6e5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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