GSM2700479[Accession] - GEO DataSets

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Items: 4

Select item 2001012211.

DNA replication-coupled histone modification maintains Polycomb gene silencing in plants

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Arabidopsis thaliana; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17639 GPL23696
18 Samples

Download data: BIGWIG, TXT

Series

Accession:: GSE101221

ID:: 200101221

PubMed Similar studies

Select item 2001012202.

DNA replication-coupled histone modification maintains Polycomb gene silencing in plants [ChIP-Rx]

(Submitter supplied) Propagation of patterns of gene expression through the cell cycle requires prompt restoration of epigenetic marks after the twofold dilution caused by DNA replication. Here, we show that the transcriptional repressive mark histone H3K27 trimethylation (H3K27me3) is restored in replicating plant cells through DNA replication-coupled modification of histone variant H3.1. Plants evolved a mechanism for efficient K27 trimethylation on H3.1, which is essential for inheritance of the silencing memory from mother to daughter cells. more...