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Items: 5

1.

HNF1b, HNF4a2 and HNF6 targets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS905
Platform:
GPL341
25 Samples
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Series
Accession:
GSE6428
ID:
200006428
2.
Full record GDS905

Pancreatic beta cell lines overexpressing wild type MODY genes or mutant HNF1b alleles

Analysis of gene expression in pancreatic beta cell line INS-1 overexpressing the transcription factors HNF1b, HNF4a2, HNF6, or mutant forms of HNF1b, which were introduced by FRT/FLP recombination. Dysfunction of these transcription factors cause maturity onset diabetes of the young (MODY).
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 5 cell line, 3 genotype/variation, 2 protocol sets
Platform:
GPL341
Series:
GSE6428
25 Samples
Download data
3.

Targets of HNF1b mutants in INS-1

(Submitter supplied) A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors HNF1b and HNF1b mutants were identified. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL341
12 Samples
Download data
Series
Accession:
GSE1590
ID:
200001590
4.

[RAE230A] Affymetrix Rat Expression 230A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...
Organism:
Rattus norvegicus
68 DataSets
148 Series
2 Related Platforms
3292 Samples
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Platform
Accession:
GPL341
ID:
100000341
5.

P328L329_del5a-

Organism:
Rattus norvegicus
Source name:
INS-1 cell line #5a with non-induced HNF1b mutant P328L329del
Platform:
GPL341
Series:
GSE1590 GSE6428
Dataset:
GDS905
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Sample
Accession:
GSM27161
ID:
300027161
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