GSM2720151[Accession] - GEO DataSets

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Items: 4

Select item 2001019901.

Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array; Genome variation profiling by high throughput sequencing

Platforms:: GPL16131 GPL17303
48 Samples

Download data: CEL, CYCHP, TSV

Series

Accession:: GSE101990

ID:: 200101990

PubMed Similar studies

Select item 2001019892.

Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition [SEQ]

(Submitter supplied) SNP arrays were combined with next generation sequencing (NGS) to precisely define the deleted region in 17 primary 11q-loss neuroblastomas and identify allelic variants in genes relevant for neuroblastoma aetiology. We assessed PARP inhibitor olaparib in combination with other chemotherapy medications using both in vitro and in vivo models.