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Items: 4

1.

Nuclear miRNA-mediated gene silencing dependent on Argonaute proteins is required for embryonic stem cell differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21493
47 Samples
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Series
Accession:
GSE108801
ID:
200108801
2.

Nuclear miRNA-mediated gene silencing dependent on Argonaute proteins is required for embryonic stem cell differentiation [5_miRNA-seq]

(Submitter supplied) Here, we show that embryonic stem cells (ESCs) and muscle stem cells contain high levels of nuclear AGO proteins and that in ESCs nuclear AGO2 protein activity is sufficient to allow for differentiation. Transcriptome-wide mapping of binding sites at nucleotide resolution revealed that nuclear AGO2 expands its target sequence repertoire in a miRNA-dependent manner to include intronic sequences to induce post-transcriptional gene silencing
Organism:
Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21493
12 Samples
Download data: XLSX
Series
Accession:
GSE108799
ID:
200108799
3.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
4.

ESC_Total_nodox_2 (5)

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL21493
Series:
GSE108799 GSE108801
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Sample
Accession:
GSM2913362
ID:
302913362
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Supplemental Content

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