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Items: 4

1.

Profiles and ChIP on chip experiments with dl1500 virus (expressing WT small e1a), R2G and deltaCR2 mutant viruses

(Submitter supplied) Adenovirus e1a induces quiescent human cells to divide. We found that e1a causes global relocalization of the RB-proteins (RB, p130, p107) and p300/CBP histone acetyltransferases on promoters that restricts H3K18ac to a limited set of genes to stimulate cell cycling and inhibit antiviral responses and cellular differentiation. Soon after expression, e1a binds transiently to cell cycle/growth genes, causing enrichment of p300/CBP, PCAF, H3K18ac, depletion of RB-proteins, and transcriptional activation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL7032 GPL7031
30 Samples
Download data: TSV, TXT
Series
Accession:
GSE12543
ID:
200012543
2.

Expression profiles and ChIP on chip genomewide experiments with dl1500 virus (expressing WT small e1a).

(Submitter supplied) Adenovirus e1a induces quiescent human cells to divide. We found that e1a causes global relocalization of the RB-proteins (RB, p130, p107) and p300/CBP histone acetyltransferases on promoters that restricts H3K18ac to a limited set of genes to stimulate cell cycling and inhibit antiviral responses and cellular differentiation. Soon after expression, e1a binds transiently to cell cycle/growth genes, causing enrichment of p300/CBP, PCAF, H3K18ac, depletion of RB-proteins, and transcriptional activation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL7031 GPL7032
19 Samples
Download data: TSV, TXT
Series
Accession:
GSE12045
ID:
200012045
3.

Human Promoter ChIP-on-chip Microarray - custom annotation

(Submitter supplied) The Human Promoter ChIP-on-chip Microarray Set is specifically designed for location analysis of human DNA-binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. Each microarray contains optimized and validated probes specifically designed for ChIP-on-chip. Coupled with Agilent's probe selection and stringent design processes, the set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. more...
Organism:
Homo sapiens
6 Series
26 Samples
Download data: TXT
Platform
Accession:
GPL7032
ID:
100007032
4.

ChIP on chip histone H4K16 acetylation (IP infected versus IP mock) at 24 hours post infection

Organism:
Homo sapiens
Source name:
IP Infected IMR90 fibroblasts (channel 1) IP Mock-infected IMR90 fibroblasts (channel 2)
Platform:
GPL7032
Series:
GSE12045 GSE12543
Download data: TSV
Sample
Accession:
GSM304367
ID:
300304367
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