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Items: 4

1.

Gene expression of CML CD34+ cells during Imatinib therapy

(Submitter supplied) Imatinib has become the current standard therapy for patients with chronic myelogenous leukaemia (CML). For a better understanding of the Imatinib-related molecular effects in vivo, we assessed gene expression profiles of Philadelphia Chromosome positive (Ph+) CD34+ cells from peripheral blood of 6 patients with de novo CML in chronic phase. After 7 days of treatment with Imatinib the Ph+ CD34+ cells were reassessed to look for changes in the transcriptome. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3518
Platform:
GPL571
12 Samples
Download data: CEL, CHP
Series
Accession:
GSE12211
ID:
200012211
2.
Full record GDS3518

Chronic myelogenous leukemia response to imatinib: Philadelphia chromosome positive CD34+ cells

Analysis of Philadelphia chromosome-positive CD34+ cells of chronic myelogenous leukemia patients treated with imatinib. The anti-cancer drug imatinib is a selective bcr-abl tyrosine kinase inhibitor. Results provide insight into the molecular events affected by bcr-abl inhibition through imatinib.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 6 individual sets
Platform:
GPL571
Series:
GSE12211
12 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3518
ID:
3518
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
641 Series
12 Related Platforms
24467 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

CML Patient 1 7 days therapy

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL571
Series:
GSE12211
Dataset:
GDS3518
Download data: CEL, CHP
Sample
Accession:
GSM307028
ID:
300307028
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