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Items: 3

1.

Mapping the heterogeneity of histone modifications on hepatitis B virus-DNA using liver needle biopsies obtained from chronically infected patients

(Submitter supplied) Covalently closed circular DNA (cccDNA) forms the basis for replication and persistence of hepatitis B virus (HBV) in the chronically infected liver. We have previously shown through the analysis of de novo HBV infected cell lines that viral transcription is subject to regulation by posttranslational modifications (PTMs) of histone proteins bound to cccDNA. We now report the successful adaptation of this ChIPseq approach for the analysis of fine-needle patient liver biopsy specimens to investigate the role of histone PTMs in chronically HBV-infected patients. more...
Organism:
Homo sapiens; Hepatitis B virus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL15520 GPL24950
179 Samples
Download data: WIG, XLSX
Series
Accession:
GSE113879
ID:
200113879
2.

Illumina MiSeq (Hepatitis B virus; Homo sapiens)

Organism:
Homo sapiens; Hepatitis B virus
1 Series
147 Samples
Download data
Platform
Accession:
GPL24950
ID:
100024950
3.

c23-H3-ChIP_2

Organism:
Hepatitis B virus; Homo sapiens
Source name:
liver
Platform:
GPL24950
Series:
GSE113879
Download data: WIG
Sample
Accession:
GSM3122316
ID:
303122316
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db=gds|term=GSM3122316[Accession]|query=1|qty=3|blobid=MCID_66742e75ccfbad768f80bdb5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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