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Items: 3

1.

HOXBLINC is aberrantly expressed in acute myeloid leukemia and functions as a potent oncogenic long non-coding RNA in leukemogenesis

(Submitter supplied) Dysregulation of HOXA/B genes is a dominant mechanism of leukemic transformation.HOXB locus-associated long non-coding RNA (lncRNAs), HOXBLINC, regulates transcription of the anterior HOXB genes and plays a critical role in hematopoiesis development. Here, we show that HOXBLINC lncRNA is up-regulated in over 60% of patients with AML. Interestingly, AML patients with high HOXBLINC expression have a significantly shortened survival as compared to low HOXBLINC expressing patients. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
5 related Platforms
40 Samples
Download data: BED, TXT
Series
Accession:
GSE115096
ID:
200115096
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

WT-RNA-seq-2

Organism:
Mus musculus
Source name:
Bone marrow Lin- Sca1+ Kit+ cells
Platform:
GPL21493
Series:
GSE115096
Download data: TXT
Sample
Accession:
GSM3165085
ID:
303165085
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