GSM3444418[Accession] - GEO DataSets

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Items: 4

Select item 2001217231.

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Expression profiling by array; Methylation profiling by genome tiling array; Methylation profiling by high throughput sequencing

5 related Platforms
364 Samples

Download data: BED, BIGWIG, BW, CEL

Series

Accession:: GSE121723

ID:: 200121723

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001217162.

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - cell line ChIPseq experiments

(Submitter supplied) Glioblastomas in adult patients are classified into four subtypes, IDH, MES, RTK I, and RTK II, based on DNA-methylation and RNA-expression data. Tumour subtype transitions are common during treatment, and transitions to the mesenchymal (MES) subtype are associated with therapy resistance and adverse prognosis. Here, we present DNA methylome and histone modification data of glioblastoma primary tumours and find that glioblastoma subtypes differ in their enhancer landscapes. more...