GSM3581130[Accession] - GEO DataSets

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Items: 4

Select item 2001257301.

Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL6246 GPL21493
20 Samples

Download data: BED, BW, CEL, XLSX

Series

Accession:: GSE125730

ID:: 200125730

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001257292.

Chromatin immunoprecipitation sequencing (ChIP-Seq) for Bhlhe40 from naïve and IL-4c-stimulated large peritoneal macrophages (LPMs)

(Submitter supplied) Most tissue-resident macrophage populations develop during embryogenesis, self-renew in the steady state, and can expand during type 2 immunity. Whether shared mechanisms regulate macrophage proliferation in homeostasis and disease is unclear. We found that the transcription factor Bhlhe40 was cell-intrinsically required in large peritoneal macrophages (LPMs) for self-renewal and maintenance, but was not required in other resident macrophages. more...