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Items: 3

1.

Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML

(Submitter supplied) Lysine Specific Demethylase 1 (LSD1 or KDM1A) is one of a number of epigenetic regulators which have recently emerged as candidate therapeutic targets in acute myeloid leukaemia (AML). Pharmacological inhibitors of LSD1 such as the tranylcypromine derivatives have already commenced evaluation in early phase clinical trials; however like all acute leukaemia therapies, it is unlikely that these inhibitors are effective as single agents. more...
Organism:
Homo sapiens; synthetic construct
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL18573 GPL19604 GPL16791
28 Samples
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Series
Accession:
GSE126486
ID:
200126486
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

in vivo BB518 RAD001 Rep2 [TS92_16_4-7]

Organism:
Homo sapiens
Source name:
in vivo BB518 RAD001
Platform:
GPL18573
Series:
GSE126486
Download data
Sample
Accession:
GSM3602447
ID:
303602447
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db=gds|term=GSM3602447[Accession]|query=1|qty=3|blobid=MCID_6795ac823ebf211704660d01|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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