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Items: 4

1.

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Caenorhabditis elegans; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL23227 GPL23479 GPL25145
57 Samples
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Series
Accession:
GSE131616
ID:
200131616
2.

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress [C. elegans]

(Submitter supplied) Organisms respond to mitochondrial stress by activating multiple defense pathways including the mitochondrial unfolded protein response (UPRmt). However, how different layers of UPRmt regulators are orchestrated to transcriptionally activate the stress responses remains largely unknown. Here we identified CBP-1, the worm ortholog of the mammalian acetyltransferases CBP/p300, as an essential regulator for UPRmt activation, as well as for mitochondrial stress-induced immune response, amyloid-β aggregation reduction and lifespan extension in Caenorhabditis elegans. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25145
27 Samples
Download data: XLSX
Series
Accession:
GSE131611
ID:
200131611
3.

BGISEQ-500 (Caenorhabditis elegans)

Organism:
Caenorhabditis elegans
36 Series
435 Samples
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Platform
Accession:
GPL25145
ID:
100025145
4.

N2 + 50% cco-1 RNAi + 50% atfs-1 RNAi_ rep1

Organism:
Caenorhabditis elegans
Source name:
N2 + 50% cco-1 RNAi + 50% atfs-1 RNAi_ rep1
Platform:
GPL25145
Series:
GSE131611 GSE131616
Download data
Sample
Accession:
GSM3790942
ID:
303790942
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Supplemental Content

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