GEO DataSets

(Submitter supplied) Chromosomal and segmental aneuploidies are usually lethal or common features of cancer cells and variety of disease, but little is known about how copy number relates to gene expression. Drosophila males have a single X chromosome and two sets of autosomes, but X chromosome and autosome transcripts are equally abundant. This 2-fold increase in X chromosome gene expression requires a dosage compensation complex (MSL) that acetylates histone 4 at lysine 16 (H4AcK16). more...

Organism:

Drosophila melanogaster

Type:

Genome variation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by array; Expression profiling by array

Platforms:

GPL8593 GPL20 GPL9058

38 Samples

Download data: FTR, GPR, TXT

(Submitter supplied) The array was assembled using amplicons representing approximately 93% of the genes predicted in version 1.0 of the Drosophila genome from sequences released by the Berkeley Drosophila Genome Project and Celera Genomics in March 2000. The amplicons represent approximately 75% of the genes predicted in the January 2003 release 3.1 Drosophila genome annotation update. Incyte in-house algorithms were used to develop gene-specific primers averaging 20 nucleotides in length that were used to PCR amplify one exon or exon fragment from every predicted gene in the fly genome. more...

Organism:

Drosophila melanogaster

8 Series

213 Samples

Download data