GSM4114154[Accession] - GEO DataSets

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Items: 4

Select item 2001386051.

Response of expanded human conventional and regulatory T cells to CD3/CD28-mediated activation (Exp1) and to CD28 or TNFR2 costimulation (Exp2)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
34 Samples

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Series

Accession:: GSE138605

ID:: 200138605

PubMed Similar studies

Select item 2001386032.

Response of expanded human conventional and regulatory T cells to CD3/CD28-mediated activation [Exp1]

(Submitter supplied) Immune responses depend on a dynamic balance between the opposing activities of conventional (Tconv) and regulatory (Treg) CD4+ T cells. While receptor-targeted approaches have been developed based on their modulation of Tconv cells, Tconv and Treg cells share many costimulatory receptors. We aim to determine key differential signaling events downstream of costimulation to find opportunities for selective manipulation of Tconv or Treg cells. more...