GSM4139674[Accession] - GEO DataSets

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Items: 3

Select item 2001393801.

Aberrant expression of RSK1 characterizes high-grade gliomas with immune infiltration

(Submitter supplied) The p90 ribosomal S6 kinase (RSK) family, a downstream target of Ras/extracellular signal-regulated kinase (ERK) signaling, can mediate cross-talk with the mammalian target of rapamycin complex 1 (mTORC1) pathway. As RSK connects two oncogenic pathways in gliomas, we investigated the protein levels of the RSK isoforms RSK1-4 in non-tumoral brain (NB) and grade I-IV gliomas. RSK4 expression was not detected in any brain tissues, whereas RSK3 expression was very low, with GBMs demonstrating the lowest RSK3 protein levels. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
30 Samples

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Accession:: GSE139380

ID:: 200139380

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000175862.

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]

(Submitter supplied) #%create_date=Wed Jan 22 15:39:59 2014 PST #%chip_type=HTA-2_0 #%lib_set_name=HTA-2_0 #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg19 #%genome-lifted_from-version-ncbi=GRCh37 #%netaffx-annotation-date=2013-10-15 #%netaffx-annotation-netaffx-build=34 Protocol: See manufacturers website