GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Methylation profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array

Platforms:

GPL3720 GPL9183 GPL3718

115 Samples

Download data: CEL, CHP

(Submitter supplied) Integrated profiling of somatic molecular alterations present in tumors is necessary to further our understanding of the tumorigenic process. We investigated the potential relationships between gene copy number alterations and DNA methylation profiles in a case series of pleural mesotheliomas (n=23). Gene copy number (CN) alterations profiled with 500K SNP arrays and DNA methylation measured at over 750 cancer-related genes with methylation bead-arrays were examined concomitantly. more...

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL9183

23 Samples

Download data: TXT

(Submitter supplied) Pathologic differentiation of tissue of origin in tumors found in the lung can be challenging, with differentiation of mesothelioma and lung adenocarcinoma emblematic of this problem. Indeed, proper classification is essential for determination of treatment regimen for these diseases, making accurate and early diagnosis critical. Here we investigate the potential of epigenetic profiles of lung adenocarcinoma, mesothelioma, and non-malignant pulmonary tissues (n=285) as differentiation markers in an analysis of DNA methylation at 1413 autosomal CpG loci associated with 773 cancer-related genes. more...

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL9183

285 Samples

Download data: TXT

(Submitter supplied) Bibikova et al. High-throughput DNA methylation profiling using universal bead arrays. Genome research 2006;16:383-93.

Organism:

Homo sapiens

40 Series

5843 Samples

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