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Items: 4

1.

Smc3 regulates B-cell transit through germinal centers and restricts their malignant transformation (Mint-ChIP)

(Submitter supplied) During the germinal center (GC) reaction, B-cells undergo extensive redistribution of cohesin complex and 3D re-organization of their genomes. Yet, the significance of cohesin and architectural programming in the humoral immune response is unknown. Herein we report that conditional homozygous deletion of cohesin subunit Smc3 abrogated GC formation, yet in marked contrast, Smc3 haploinsufficiency induced GC hyperplasia, skewing of GC polarity and impaired plasma cell differentiation. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
6 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE146753
ID:
200146753

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Smc3 regulates B-cell transit through germinal centers and restricts their malignant transformation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Other; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL17021
29 Samples
Download data: CSV, MCOOL
Series
Accession:
GSE143852
ID:
200143852

PubMed Full text in PMC Similar studies

3.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10368 Series
297601 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

4.

H3K27Ac ChIP centroblast Cγ1-cre 3

Organism:
Mus musculus
Source name:
germinal center centrocytes from spleen
Platform:
GPL19057
Series:
GSE143852 GSE146753
Download data
Sample
Accession:
GSM4405423
ID:
304405423

SRA Run Selector

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db=gds|term=GSM4405423[Accession]|query=1|qty=2|blobid=MCID_6759b9dedf415c74f8062621|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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