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Items: 3

1.

Custom DNA microarrays reveal the selective recognition of BMVC to MYC promoter G-quadruplex: a large-scale assessment of ligand binding selectivity

(Submitter supplied) G-quadruplexes (G4) are considered new drug targets for human diseases such as cancer. More than 10,000 G4s have been discovered in human chromatin, posing challenges for assessing the selectivity of a G4-interactive ligand. 3,6-bis(1-Methyl-4-vinylpyridinium) carbazole diiodide (BMVC) is the first fluorescent small molecule for G4 detection in vivo. Our previous structural study shows that BMVC binds to the MYC promoter G4 (MycG4) with high specificity. more...
Organism:
synthetic construct
Type:
Other
Platform:
GPL28372
12 Samples
Download data: TXT
Series
Accession:
GSE148419
ID:
200148419
2.

Agilent-086005 ASSAD_G4_D4 G4125A array

(Submitter supplied) see manufacturer's web site at http://www.agilent.com/
Organism:
synthetic construct
1 Series
12 Samples
Download data: TXT
Platform
Accession:
GPL28372
ID:
100028372
3.

G4_d4_Cy5-PDS_1uM_plus_3uM_BMVC_comp_rep2

Organism:
synthetic construct
Source name:
1uM Cy5-PDS + 3uM BMVC, G4 design 4
Platform:
GPL28372
Series:
GSE148419
Download data: TXT
Sample
Accession:
GSM4469946
ID:
304469946
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