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Items: 4

1.

Network-based assessment of HDAC6 activity is highly predictive of pre-clinical and clinical responses to the HDAC6 inhibitor ricolinostat

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
4 related Platforms
73 Samples
Download data: TXT
Series
Accession:
GSE180607
ID:
200180607
2.

Network-based assessment of HDAC6 activity is highly predictive of pre-clinical and clinical responses to the HDAC6 inhibitor ricolinostat [high throughput sequencing]

(Submitter supplied) Despite the anticancer activity of pan-histone deacetylase (HDAC) inhibitors, their clinical use has been limited due to toxicity. However, the development of more specific inhibitors that selectively inhibit individual HDACs is emerging as a novel and well-tolerated alternative. Here, we present the results of the first clinical trial evaluating the activity of ricolinostat (the leading HDAC6 inhibitor) in breast cancer (BC) patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL16791
43 Samples
Download data: TXT
Series
Accession:
GSE148623
ID:
200148623
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

pt14

Organism:
Homo sapiens
Source name:
ductal breast cancer tissue
Platform:
GPL16791
Series:
GSE148623 GSE180607
Download data: TXT
Sample
Accession:
GSM4475390
ID:
304475390
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Supplemental Content

db=gds|term=GSM4475390[Accession]|query=1|qty=3|blobid=MCID_6732f8265276a9560a587053|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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