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Items: 4

1.

Gene expression profile of primary CLL cells transduced with a mutated NOTCH1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL16791 GPL20301 GPL24676
82 Samples
Download data: BED
Series
Accession:
GSE150610
ID:
200150610
2.

Gene expression profile of primary CLL cells transduced with a mutated form on NOTCH1 following IgM stimulation

(Submitter supplied) In CLL, NOTCH1 is the most commonly mutated gene at diagnosis and it is associated with a poor outcome. The mechanisms underlying how NOTCH1 contributes to disease progression, resistance to treatment and Richter’s transformation remain largely unknown. Data suggests a link between BCR activation and NOTCH1 signalling so the main goal of this study is to compare the gene expression profile of primary CLL cells transduced with the intracellular part of NOTCH1 lacking of the PEST domain vs cells transduced with an empty vector following IgM stimulation.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20301
20 Samples
Download data: CSV
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

P2_NOTCH

Organism:
Homo sapiens
Source name:
primary CLL cells
Platform:
GPL20301
Series:
GSE150595 GSE150610
Download data
Sample
Accession:
GSM4552936
ID:
304552936
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Supplemental Content

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