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Items: 3

1.

Substrate Identification Using a Chemical Genetics Approach Reveals a Role for PARP-7-Mediated MARylation in Controlling Microtubule Stability in Ovarian Cancer Cells

(Submitter supplied) ADP-ribosylation (ADPRylation) is a regulatory posttranslational modification of proteins that results in the covalent attachment of ADP-ribose (ADPR) moieties on target proteins. PARP-7 (TiPARP) is a monoADPR transferase whose proteins substrates and biological activities are poorly understood. Here, we describe a chemical genetics approach that has allowed us to identify substrates of PARP-7 and explore their biological functions. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
8 Samples
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2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

PARP 7 KD with SiRNA 2 Replicate 1

Organism:
Homo sapiens
Source name:
PARP 7 KD with siRNA 2
Platform:
GPL11154
Series:
GSE153395
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Sample
Accession:
GSM4643503
ID:
304643503
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db=gds|term=GSM4643503[Accession]|query=1|qty=2|blobid=MCID_6700294375ef19692973e5bc|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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