GSM4774850[Accession] - GEO DataSets

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Items: 4

Select item 2001577721.

Molecular signatures of immune cells and neuroblasts in the aged brain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
10 Samples

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Series

Accession:: GSE157772

ID:: 200157772

PubMed Similar studies

Select item 2001577712.

Molecular signatures of immune cells and neuroblasts in the aged brain

(Submitter supplied) Normal aging is accompanied by escalating systemic inflammation. To comprehensively characterize the impact of aging on immune cells in the brain and periphery, we harvested immune cells from mouse spleen and brain tissues. Single cell sequencing was performed to compare the genetic signatures in these isolated immune cell subsets from spleen and brain tissues in young and aged mice. Our results demonstrate increased accumulations of immune cells such as natural killer (NK) cells in the aged brain as compared to the young brain. more...