GSM4795517[Accession] - GEO DataSets

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Items: 4

Select item 2001582231.

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Other; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL24247
60 Samples

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Series

Accession:: GSE158223

ID:: 200158223

PubMed Full text in PMC Similar studies

Select item 2001582222.

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity [Bisulfite-Seq]

(Submitter supplied) Treg cells bearing a diverse antigen receptor repertoire suppress pathogenic T cells and maintain immune homeostasis during their long lifespan. How their robust function is determined genetically remains elusive. Here, we investigate the regulatory space of the cis-regulatory elements of Treg lineage–specifying factor Foxp3. Foxp3 enhancers are known as distinct readers for environmental cues in promoting Treg cell induction or lineage stability. more...

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL24247
8 Samples

Download data: BW

Series

Accession:: GSE158222

ID:: 200158222

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000242473.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

13930 Series
690072 Samples

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Accession:: GPL24247

ID:: 100024247

Select item 3047955174.

WGBS-regulatory T cells- Foxp3 enhancer CNS0 knockout-replicate 2

Organism:: Mus musculus

Source name:: Regulatory T cells were sorted by GFP expression from mixed bone marrow chimeric mice generated with bone marrows from male donors of CD45.1 wild-type mice and CD45.2 mice of indicated genotypes