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Items: 3

1.

HDAC inhibitors result in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies 

(Submitter supplied) Histone acetylation is associated with active transcription and serves as a binding site for reader proteins that function in transcriptional initiation and elongation. Histone acetylation levels are regulated through the actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs) that antagonistically control the overall balance of this posttranslational modification. HDAC inhibitors (HDACi) are potent agents that disrupt this balance and are used clinically to treat a range of human diseases including cancer. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
30 Samples
Download data: BW, TXT
Series
Accession:
GSE159620
ID:
200159620

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12466 Series
340425 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

JQ1_RNA_Rep3

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835953
ID:
304835953

SRA Run Selector

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db=gds|term=GSM4835953[Accession]|query=1|qty=2|blobid=MCID_670cd8c7c7d3ca20d5b6dc60|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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