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Items: 3

1.

scRNA-seq profiling of breast cancer tumors, BRCA1 mutant pre-neoplastic mammary gland cells and normal mammary gland cells

(Submitter supplied) This study presents a single cell transcriptome map of nearly 430,000 cells encompassing normal breast at different hormonal stages, preneoplastic BRCA1+/- tissue, the major clinical subtypes of breast cancer, and matching pairs of tumors and involved axillary lymph nodes. Comparison of normal tissue specimens according to menopausal status primarily revealed changes in the stroma. Although there were modest changes in the microenvironment of preneoplastic BRCA1+/- versus normal tissue, a profound increase in infiltrating immune cells and a concomitant decrease in fibroblasts accompanied the transition to neoplasia. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
69 Samples
Download data: MTX, TSV
Series
Accession:
GSE161529
ID:
200161529
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Normal Total cells from Patient 0021

Organism:
Homo sapiens
Source name:
Mammary gland
Platform:
GPL18573
Series:
GSE161529
Download data: MTX, TSV
Sample
Accession:
GSM4909272
ID:
304909272
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Supplemental Content

db=gds|term=GSM4909272[Accession]|query=1|qty=2|blobid=MCID_666e5385909a3d46adb7c231|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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