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Items: 4

1.

DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL24973 GPL17021 GPL24247
111 Samples
Download data: BW
Series
Accession:
GSE161822
ID:
200161822
2.

DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

(Submitter supplied) Chromosomal translocations result from the joining of DNA double-strand breaks (DSBs) and frequentlycause cancer. However, the steps linking DSB formation to DSB ligation remain undeciphered. Wereport that DNA replication timing (RT) directly regulates lymphomagenicMyctranslocations duringantibody maturation in B cells downstream of DSBs and independently of DSB frequency. Depletion ofminichromosome maintenance complexes alters replication origin activity, decreases translocations,and deregulates global RT. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL24973
44 Samples
Download data: TXT
Series
Accession:
GSE161818
ID:
200161818
3.

MinION (Mus musculus)

Organism:
Mus musculus
56 Series
378 Samples
Download data
Platform
Accession:
GPL24973
ID:
100024973
4.

CH12_LAM-HTGTS_shMcm_rep1

Organism:
Mus musculus
Source name:
CH12
Platform:
GPL24973
Series:
GSE161818 GSE161822
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Sample
Accession:
GSM4915160
ID:
304915160
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