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Items: 3

1.

Systematic phenotypic characterization and integrated analysis show heterogeneous neomorphic activities of different missense mutant p53 proteins

(Submitter supplied) The phenotypic and transcriptomic data on ten normal breast epithelial cell lines each expressing a distinct missense mutant p53 protein, and their systems-level analysis through ChIP-Seq and RNA-seq defines the molecular basis for phenotypic heterogeneity imparted by the different missense mutant p53 proteins. The focus of the study is to gain mechanistic insight on the neomorphic function of mutant p53 proteins and their manifestation into phenotypic heterogeneity in the context of a TNBC model.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
23 Samples
Download data: CSV, NARROWPEAK
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

MCF10A p53 R273H mutant cells - ChIP-Seq - input DNA

Organism:
Homo sapiens
Source name:
ectopic expression of p53 R273H mutant protein with V5 tag at C-term
Platform:
GPL18573
Series:
GSE162341
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Sample
Accession:
GSM4950005
ID:
304950005
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db=gds|term=GSM4950005[Accession]|query=1|qty=2|blobid=MCID_6623845b4c13c13a064a016c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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