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Items: 3

1.

Development of a transcriptomic biomarker to detect histone deacetylase inhibitors (HDACi) in TK6 cells

(Submitter supplied) Transcriptomic signatures, or biomarkers, of toxicity can facilitate rapid mechanistic analysis of chemicals using high-content transcriptomic data and identification of potential hazards to human health. We developed an 81-gene transcriptomic biomarker, named TGx-HDACi, to detect histone deacetylase inhibitors (HDACi) in TK6 human lymphoblastoid cells after 4 hours of chemical exposure. This work leveraged an established transcriptomic biomarker of DNA damage, TGx-DDI, which was developed by Heng Hong Li et al. more...
Organism:
blank sample; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL29107 GPL18573
128 Samples
Download data: TXT
Series
Accession:
GSE164478
ID:
200164478
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Sample 121_Plate 2_Universal human reference RNA_Rep 1

Organism:
Homo sapiens
Source name:
Plate 2_Universal human reference RNA
Platform:
GPL18573
Series:
GSE164478
Download data
Sample
Accession:
GSM5011956
ID:
305011956
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