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Items: 4

1.

Transcriptional profiling of brain tissues from a Q130 Long Evans Knock-in rat model of Huntington’s disease at 10-, 19- and 24-months of age

(Submitter supplied) Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric alterations. The mutation responsible for this disease is an abnormally expanded and unstable CAG repeat within the coding region of the gene encoding huntingtin (Htt). A collaboration between the CHDI Foundation and Dr. H.P. Nguyen (huu.nguyen-r7w@ruhr-uni-bochum.de) at Universitat Bochum focused on generating a knock-in rat model of HD that contains expanded CAG repeats inserted within the rat huntingtin gene (Hdh) in order to provide a genetic reconstruction of the human causative mutation within the rat model. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25947
145 Samples
Download data: TXT
Series
Accession:
GSE169386
ID:
200169386
2.

Transcriptional profiling of brain tissues from a Q130 Long Evans Knock-in rat model of Huntington’s disease at 2-, 6-, 10-, 12-, 19- and 24-months of age

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL25947 GPL14844
397 Samples
Download data
Series
Accession:
GSE169388
ID:
200169388
3.

Illumina NovaSeq 6000 (Rattus norvegicus)

Organism:
Rattus norvegicus
602 Series
12522 Samples
Download data
Platform
Accession:
GPL25947
ID:
100025947
4.

WT Cortex 10 months male mRNA rep1 [10_19_24_mo]

Organism:
Rattus norvegicus
Source name:
Cortex
Platform:
GPL25947
Series:
GSE169386 GSE169388
Download data
Sample
Accession:
GSM5201416
ID:
305201416
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