GSM523199[Accession] - GEO DataSets

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Items: 3

Select item 2000209121.

p53-mediated hematopoietic stem and progenitor cell competition

(Submitter supplied) Cell competition was originally described in Drosophila as a process for selection of the fittest cells. Using genetic mosaic mouse models and bone marrow chimeras, we have characterized a form of cell competition that selects for the least damaged cells. This competition is controlled by p53 but is distinct from the classical p53-mediated DNA damage response: it persists for months, is specific to the hematopoietic stem and progenitor cells, and depends on the relative rather than absolute level of p53 in competing cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6105
12 Samples

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Accession:: GSE20912

ID:: 200020912

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000061052.

Illumina mouse-6 v1.1 expression beadchip

(Submitter supplied) The MouseWG-6 v1.1 Expression BeadChip contains six wholegenome gene expression arrays allowing six samples to be hybridized to a single chip. BeadChip content was created by combining proven sources, including the Mouse Exonic Evidence Based Oligonucleotide (MEEBO) set, the RIKEN FANTOM 22-5 database, and the National Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) database. more...