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Items: 3

1.

A genetic mouse model of malignant peripheral nerve sheath tumor with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human tumors

(Submitter supplied) We established a new genetically engineered mouse (GEM) model of malignant peripheral nerve sheath tumors (MPNST) based on postnatal deletion of a Nf1;Trp53 cis-conditional allele by the tamoxifen-inducible Plp-CreER (NP-Plp). We also generated two Lats1;2 conditional knockout models by using Nestin-Cre (Lats-Nes) and Plp-CreER (Lats-Plp), both of which also develop tumors similar to MPNST (GEM-PNST). more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL24676
44 Samples
Download data: TXT
Series
Accession:
GSE172221
ID:
200172221
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Lats-Nes Tumor 4 Grade UD

Organism:
Mus musculus
Source name:
Tumor tissue
Platform:
GPL24247
Series:
GSE172221
Download data: TXT
Sample
Accession:
GSM5244254
ID:
305244254
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db=gds|term=GSM5244254[Accession]|query=1|qty=3|blobid=MCID_66fb5f8f8c49702d71e30fea|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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