GSM544293[Accession] - GEO DataSets

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Items: 3

Select item 2000218911.

Expression data from insulin-treated human primary fibroblasts and effects of U0126 on insulin-induced gene expression

(Submitter supplied) We carried out a high throughput analysis of insulin-induced kinase signaling pathways in primary fibroblasts from 35 unrelated individuals. We found that extensive individual variation exists in induction of various signaling pathways. ERK signaling displayed the greatest variation, which led to extensive variation in expression of downstream target genes. Our results suggest that phenotypic variation in kinase signaling mediates variation in downstream processes of insulin response. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL571
129 Samples

Download data: CEL, CHP, TXT, XLSX

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Accession:: GSE21891

ID:: 200021891

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000005712.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...