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Items: 4

1.

Germ-cell specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation [RNA-seq]

(Submitter supplied) Translation of maternal mRNAs is detected before transcription of zygotic genes and is essential for mammalian embryo development. How certain maternal mRNAs are selected for translation instead of degradation and how this burst of translation affects zygotic genome activation remains unknown. Using gene-edited mice, we document that the oocyte-specific eukaryotic translation initiation factor 4E family member 1b (eIF4E1b) is the regulator of maternal mRNA expression that ensures subsequent reprogramming of the zygotic genome. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
371 Samples
Download data: CSV, TSV
Series
Accession:
GSE180206
ID:
200180206
2.

Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation

(Submitter supplied) Translation of maternal mRNAs is detected before transcription of zygotic genes and is essential for mammalian embryo development. How certain maternal mRNAs are selected for translation instead of degradation and how this burst of translation affects zygotic genome activation remain unknown. Using gene-edited mice, we document that the oocyte-specific eukaryotic translation initiation factor 4E family member 1b (eIF4E1b) is the regulator of maternal mRNA expression that ensures subsequent reprogramming of the zygotic genome. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other
Platforms:
GPL21103 GPL24247
602 Samples
Download data: BW, TSV
Series
Accession:
GSE180218
ID:
200180218
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

M2_Het_A3W_5

Organism:
Mus musculus
Source name:
single M2 egg
Platform:
GPL21103
Series:
GSE180206 GSE180218
Download data: TSV
Sample
Accession:
GSM5455569
ID:
305455569
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Supplemental Content

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