GSM5473832[Accession] - GEO DataSets

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Items: 3

Select item 2001808651.

GNL3/nucleostemin links DNA replication homeostasis and replication forks stability

(Submitter supplied) The regulation of replication forks stalling and replication origins firing must be tightly coordinated to prevents genomic instability. Here we show that GNL3/nucleostemin, a GTP-binding protein able to shuttle between the nucleolus and the nucleoplasm, limits replicative stress by limiting replication origins firing. GNL3 is in proximity of nascent DNA and its depletion reduces forks speed but increases forks density and replication origins firing. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platform:: GPL10123
6 Samples

Download data: TXT

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Accession:: GSE180865

ID:: 200180865

Analyze with GEO2R

Select item 1000101232.

Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)

(Submitter supplied) SurePrint G3 Human CGH Microarray 4x180K Arrays of this design have barcodes that begin with 16022060 or 2522060. Data table annotations based on build hg18:NCBI36:Mar2006. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...